Leo will line up in the first Florida derby match of his MLS career as Inter Miami prepare to lock horns with Orlando City at Chase Stadium on Saturday.
The Argentine faced Los Leones once last season, in a League's Cup encounter in which Inter, the eventual competition winners, came out on top and Leo bagged a brace.
The Miami-based outfit come into the clash sitting at the top of the MLS standings after the opening two games, while Orlando City lie in 11th spot after claiming a point in their season opener.